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Mechanisms of the inhibition of endplate acetylcholine receptors by antiseptic chlorhexidine (experiments and models)

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    SYSNO ASEP0333517
    Document TypeJ - Journal Article
    R&D Document TypeJournal Article
    Subsidiary JČlánek ve WOS
    TitleMechanisms of the inhibition of endplate acetylcholine receptors by antiseptic chlorhexidine (experiments and models)
    TitleMechanismus inhibice ploténkových acetylcholinových receptorů antiseptikem chlorhexidinem
    Author(s) Shaihutdinova, A.R. (RU)
    Nikolsky, E. E. (RU)
    Vyskočil, František (FGU-C) RID
    Skorinkin, A.I. (RU)
    Source TitleNaunyn-Schmiedeberg's Archives of Pharmacology. - : Springer - ISSN 0028-1298
    Roč. 380, č. 6 (2009), s. 551-560
    Number of pages10 s.
    Languageeng - English
    CountryDE - Germany
    Keywordsacetylcholine ; endplate currents
    Subject RIVED - Physiology
    R&D ProjectsIAA500110905 GA AV ČR - Academy of Sciences of the Czech Republic (AV ČR)
    CEZAV0Z50110509 - FGU-C (2005-2011)
    UT WOS000272046000009
    DOI10.1007/s00210-009-0458-0
    AnnotationGiven the very widespread use of antiseptics chlorhexidine in surgery, infant and communal hygiene, the publication of the findings irreversibilní inhibition of neuromuscular disc model and explanation of its action to be taken into account when assessing the side-effects in the normal application of chlorhexidine, and an explanation of fatal cases after an inadvertent overdosage and systemic administration
    WorkplaceInstitute of Physiology
    ContactLucie Trajhanová, lucie.trajhanova@fgu.cas.cz, Tel.: 241 062 400
    Year of Publishing2010
Number of the records: 1  

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