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Norbornane as the novel pseudoglycone moiety in nucleosides
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SYSNO ASEP 0331982 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title Norbornane as the novel pseudoglycone moiety in nucleosides Author(s) Šála, Michal (UOCHB-X) RID, ORCID
Hřebabecký, Hubert (UOCHB-X) RID, ORCID
Dračínský, Martin (UOCHB-X) RID, ORCID
Masojídková, Milena (UOCHB-X)
De Palma, A. (BE)
Neyts, J. (BE)
Holý, Antonín (UOCHB-X)Number of authors 7 Source Title Tetrahedron. - : Elsevier - ISSN 0040-4020
Roč. 65, č. 45 (2009), s. 9291-9299Number of pages 9 s. Language eng - English Country GB - United Kingdom Keywords carbocyclic nucleosides ; norbornane ; coxsackie virus Subject RIV CC - Organic Chemistry R&D Projects 1M0508 GA MŠMT - Ministry of Education, Youth and Sports (MEYS) 1QS400550501 GA AV ČR - Academy of Sciences of the Czech Republic (AV ČR) CEZ AV0Z40550506 - UOCHB-X (2005-2011) UT WOS 000271094000030 DOI 10.1016/j.tet.2009.09.018 Annotation This study concerns synthesis of novel racemic conformationally locked nucleosides with bicyclo[2.2.1]heptene or heptane ring system substituted with nucleobase at position 7 and with the anti-configuration of the nucleobase. Biological activity of the newly prepared compounds is described. Activity against Coxsackie B3 virus is discussed. Workplace Institute of Organic Chemistry and Biochemistry Contact asep@uochb.cas.cz ; Kateřina Šperková, Tel.: 232 002 584 ; Viktorie Chládková, Tel.: 232 002 434 Year of Publishing 2010
Number of the records: 1