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Resveratrol attenuates lipopolysaccharide-induced hepatitis in D-Galactosamine sensitized rats: Role of nitric oxide synthase 2 and heme oxygenase-1
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SYSNO ASEP 0330496 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title Resveratrol attenuates lipopolysaccharide-induced hepatitis in D-Galactosamine sensitized rats: Role of nitric oxide synthase 2 and heme oxygenase-1 Author(s) Farghali, H. (CZ)
Černý, D. (CZ)
Kameníková, L. (CZ)
Martínek, J. (CZ)
Hořínek, A. (CZ)
Kmoníčková, Eva (UEM-P) RID
Zídek, Zdeněk (UEM-P)Source Title Nitric Oxide-Biology and Chemistry. - : Elsevier - ISSN 1089-8603
Roč. 21, 3-4 (2009), s. 216-225Number of pages 10 s. Language eng - English Country NL - Netherlands Keywords resveratrol ; lipopolysacchride ; nitrix oxide Subject RIV FR - Pharmacology ; Medidal Chemistry R&D Projects GA305/07/0061 GA ČR - Czech Science Foundation (CSF) CEZ AV0Z50390512 - UEM-P (2005-2011) UT WOS 000272267600010 DOI 10.1016/j.niox.2009.09.004 Annotation Resveratrol improves hepatotoxic markers and morphology after the hepatic insult. Among the mechanisms responsible for the hepatoprotective effects of resveratrol are reduction of NO production, downeregulation of nitric oxide synthese, madification of oxidative stress parameters and modulation of heme oxygenase-1. Workplace Institute of Experimental Medicine Contact Lenka Koželská, lenka.kozelska@iem.cas.cz, Tel.: 241 062 218, 296 442 218 Year of Publishing 2010
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