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Do GST Polymorphisms Modulate the Frequency of Chromosomal Aberrations in Healthy Subjects?
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SYSNO ASEP 0330483 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title Do GST Polymorphisms Modulate the Frequency of Chromosomal Aberrations in Healthy Subjects? Title Moduluje GST polymorfizmus frekvenci chromozomálních aberací? Author(s) Vodička, Pavel (UEM-P) RID
Naccarati, Alessio (UEM-P)
Vodičková, Ludmila (UEM-P) RID
Poláková, Veronika (UEM-P) RID
Dušinská, M. (SK)
Mušák, L. (SK)
Halasová, E. (SK)
Susová, S. (CZ)
Souček, P. (CZ)
Hemminki, K. (DE)Source Title Environmental Health Perspectives. - : U.S. Department of Health and Human Services - ISSN 0091-6765
Roč. 117, č. 9 (2009), A384-A385Number of pages 2 s. Language eng - English Country US - United States Keywords DNA-repair genes ; individual susceptibility ; biomarkers Subject RIV EB - Genetics ; Molecular Biology CEZ AV0Z50390512 - UEM-P (2005-2011) UT WOS 000269479900002 DOI 10.1289/ehp.0900838 Annotation Rossi et al. (2009) described an association between chromosomal aberration (CA) frequency and cancer risk in a case–control study on 107 cancer cases and 291 controls, whereby they observed no modifying effect of polymorphisms in glutathione S transferase M1 (GSTM1) and GSTT1. In our studies of 488 healthy individuals from Slovakia and the Czech Republic, we observed a CA frequency of 2.35 ± 1.73 (mean ± SD). Workplace Institute of Experimental Medicine Contact Lenka Koželská, lenka.kozelska@iem.cas.cz, Tel.: 241 062 218, 296 442 218 Year of Publishing 2010
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