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Urinary 8-oxodeoxyguanosine levels in children exposed to air pollutants
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SYSNO ASEP 0330440 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title Urinary 8-oxodeoxyguanosine levels in children exposed to air pollutants Title Hladina 8-oxodeoxyguanosinu v moči dětí exponovaných znečištěnému ovzduší Author(s) Švecová, Vlasta (UEM-P) RID
Rössner ml., Pavel (UEM-P) RID, ORCID
Dostál, Miroslav (UEM-P) RID
Topinka, Jan (UEM-P) RID, ORCID
Solanský, I. (CZ)
Šrám, Radim (UEM-P) RIDSource Title Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. - : Elsevier - ISSN 0027-5107
Roč. 662, 1-2 (2009), s. 37-43Number of pages 7 s. Language eng - English Country NL - Netherlands Keywords air pollution ; child health ; oxidative stress Subject RIV DN - Health Impact of the Environment Quality R&D Projects SL/5/160/05 GA MŽP - Ministry of Environment (MŽP) SP/1B3/50/07 GA MŽP - Ministry of Environment (MŽP) CEZ AV0Z50390512 - UEM-P (2005-2011) UT WOS 000264580800008 DOI 10.1016/j.mrfmmm.2008.12.003 Annotation The levels of 8-oxodeoxyguanosine (8-oxodG), a marker of oxidative damage to DNA, in urine samples of 894 children were meaured using an ELISA technique. It was found the association between 8-oxodG levels and the exposure to air particulate matter PM10 and PM2.5, carcinogenic PAHs as well as individual lifestyle and environmental tobacco smoke. The obtained results indicate that 8-oxodG is a sensitive biomarker for measuring the exposure of children to air pollution. Workplace Institute of Experimental Medicine Contact Lenka Koželská, lenka.kozelska@iem.cas.cz, Tel.: 241 062 218, 296 442 218 Year of Publishing 2010
Number of the records: 1