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Effect of vitamin levels on biomarkers of exposure and oxidative damage – The EXPAH study

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    SYSNO ASEP0330426
    Document TypeJ - Journal Article
    R&D Document TypeJournal Article
    Subsidiary JČlánek ve WOS
    TitleEffect of vitamin levels on biomarkers of exposure and oxidative damage – The EXPAH study
    TitleVliv hladiny vitamínů na biomarkery expozice a oxidační poškození – Studie EXPAH
    Author(s) Šrám, Radim (UEM-P) RID
    Farmer, P. (GB)
    Singh, R. (GB)
    Garte, S. (IT)
    Kalina, I. (US)
    Popov, T. A. (BG)
    Binková, Blanka (UEM-P)
    Ragin, C. (US)
    Taioli, E. (US)
    Source TitleMutation Research - Genetic Toxicology and Environmental Mutagenesis. - : Elsevier - ISSN 1383-5718
    Roč. 672, č. 2 (2009), s. 129-134
    Number of pages6 s.
    Languageeng - English
    CountryNL - Netherlands
    Keywordsmolecular epidemiology ; cross-sectional study ; biomarkers of exposure
    Subject RIVDN - Health Impact of the Environment Quality
    CEZAV0Z50390512 - UEM-P (2005-2011)
    UT WOS000263747900010
    DOI10.1016/j.mrgentox.2008.11.005
    AnnotationThe objective of the study was to assess if there is a relationship between vitamins A, C and E, which are known to play a significant role as antioxidant agents, and biomarkers of genotoxicity and oxidative stress. A significant inverse correlation was observed between plasma vitamin levels and both B[a]P and bulky DNA adducts. Vitamin A was also significantly inversely correlated with M1dG, a marker of oxidative damage. The associations were stronger in non-smokers than in smokers.
    WorkplaceInstitute of Experimental Medicine
    ContactLenka Koželská, lenka.kozelska@iem.cas.cz, Tel.: 241 062 218, 296 442 218
    Year of Publishing2010
Number of the records: 1  

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