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Concentrations of some metabolites in the breath of healthy children aged 7–18 years measured using selected ion flow tube mass spectrometry (SIFT-MS)
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SYSNO ASEP 0329754 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Ostatní články Title Concentrations of some metabolites in the breath of healthy children aged 7–18 years measured using selected ion flow tube mass spectrometry (SIFT-MS) Title Koncentrace některých metabolitů v dechu zdravých dětí ve věku od 7 do 18 let měřené pomocí hmotnostní spektrometrie v proudové trubici s vybranými ionty (SIFT-MS) Author(s) Enderby, B. (GB)
Lenney, W. (GB)
Brady, M. (GB)
Emmett, C. (GB)
Španěl, Patrik (UFCH-W) RID, ORCID
Smith, D. (GB)Source Title Journal of Breath Research. - : Institute of Physics Publishing - ISSN 1752-7155
Roč. 3, č. 3 (2009), 036001Number of pages 11 s. Language eng - English Country GB - United Kingdom Keywords SIFT-MS ; breath analysis Subject RIV CF - Physical ; Theoretical Chemistry CEZ AV0Z40400503 - UFCH-W (2005-2011) DOI 10.1088/1752-7155/3/3/036001 Annotation Using selected ion flow tube mass spectrometry (SIFT-MS), measurements have been made of the levels of several metabolites in the exhaled breath of 200 healthy school children. Thus, concentration distributions of each metabolite have been obtained for the first time in the paediatric age range. The median values (in parentheses) of the concentrations in parts per billion, ppb, were ammonia (628), acetone (297), methanol (193), ethanol (187), isoprene (37), propanol (16), acetaldehyde (23) and pentanol (15). Hydrogen cyanide was not present in the breath above the detection limit of 2 ppb in the majority of subjects. The water vapour level (humidity) of the breath samples was routinely measured as a check on the sample integrity. Such data are essential if SIFT-MS breath analyses are to be used as a clinical tool to aid diagnosis and/or as a monitor of disease in children. Workplace J. Heyrovsky Institute of Physical Chemistry Contact Michaela Knapová, michaela.knapova@jh-inst.cas.cz, Tel.: 266 053 196 Year of Publishing 2010
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