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The quantification of carbon dioxide in humid air and exhaled breath by selected ion flow tube mass spectrometry

SYSNO ASEP	0329750
Document Type	J - Journal Article
R&D Document Type	Journal Article
Subsidiary J	Článek ve WOS
Title	The quantification of carbon dioxide in humid air and exhaled breath by selected ion flow tube mass spectrometry
Title	Kvantifikace oxidu uhličitého ve vlhkém vzduchu a dechu pomocí hmotnostní spektrometrie v proudové trubici s vybranými ionty (SIFT-MS)
Author(s)	Smith, D. (GB) Pysanenko, A. (GB) Španěl, Patrik (UFCH-W)_{RID, ORCID}
Source Title	Rapid Communications in Mass Spectrometry. - : Wiley - ISSN 0951-4198 Roč. 23, č. 10 (2009), s. 1419-1425
Number of pages	7 s.
Language	eng - English
Country	GB - United Kingdom
Keywords	trace gras-analysis ; quantitative analysis ; SIFT-MS
Subject RIV	CF - Physical ; Theoretical Chemistry
R&D Projects	GA203/09/0256 GA ČR - Czech Science Foundation (CSF)
	GA202/09/0800 GA ČR - Czech Science Foundation (CSF)
CEZ	AV0Z40400503 - UFCH-W (2005-2011)
UT WOS	000265985000003
DOI	10.1002/rcm.4016
Annotation	The reactions of carbon dioxide, CO2, with the precursor ions used for selected ion flow tube mass spectrometry, SIFT-MS, analyses, viz. H3O+, NO+ and O2+, are so slow that the presence of CO2 in exhaled breath has, until recently, not had to be accounted for in SIFT-MS analyses of breath. This has, however, to be accounted for in the analysis of acetaldehyde in breath, because an overlap occurs of the monohydrate of protonated acetaldehyde and the weakly bound adduct ion, H3O+CO2, formed by the slow association reaction of the precursor ion H3O+ with CO2 molecules. The understanding of the kinetics of formation and the loss rates of the relevant ions gained from experimentation using the new generation of more sensitive SIFT-MS instruments now allows accurate quantification of CO2 in breath using the level of the H3O+CO2 adduct ion. However, this is complicated by the rapid reaction of H3O+CO2 with water vapour molecules, H2O, that are in abundance in exhaled breath.
Workplace	J. Heyrovsky Institute of Physical Chemistry
Contact	Michaela Knapová, michaela.knapova@jh-inst.cas.cz, Tel.: 266 053 196
Year of Publishing	2010

Number of the records: 1