Number of the records: 1

Mathematical Modeling of Chondrocyte Proliferation on Nanofibrous Scaffolds. Theoretical Analysis and Experiments

SYSNO ASEP	0329509
Document Type	C - Proceedings Paper (int. conf.)
R&D Document Type	Conference Paper
Title	Mathematical Modeling of Chondrocyte Proliferation on Nanofibrous Scaffolds. Theoretical Analysis and Experiments
Author(s)	Maršík, František (UT-L)_RID Filová, Eva (UEM-P)_{RID, ORCID} Kozák, J. (CZ) Klika, Václav (UT-L)_RID Martinová, L. (CZ) Lukáš, D. (CZ) Michálek, Jiří (UMCH-V)_{RID, ORCID} Přádný, Martin (UMCH-V)_RID Amler, Evžen (UEM-P)_RID
Number of authors	9
Source Title	ICTE 2009 International Conference on Tissue Engineering an Eccomas Thematic Conference. - Leiria : Polytechnic Institute of Leiria, 2009 / Bártolo P.J. ; Fernandes P.R. ; Ruben R.B. ; Folgado J. ; Almeida H. ; Alves N. ; Mendes A. - ISBN 978-972-8469-90-0
Pages	s. 123-130
Number of pages	8 s.
Action	ICTE 2009 International Conference on Tissue Engineering an Eccomas Thematic Conference
Event date	09.07.2009-11.07.2009
VEvent location	Leiria
Country	PT - Portugal
Event type	WRD
Language	eng - English
Country	PT - Portugal
Keywords	tissue Engineering ; scaffold ; biomaterials
Subject RIV	FI - Traumatology, Orthopedics
R&D Projects	IAA500390702 GA AV ČR - Academy of Sciences of the Czech Republic (AV ČR)
	2B06130 GA MŠMT - Ministry of Education, Youth and Sports (MEYS)
	GA106/08/0557 GA ČR - Czech Science Foundation (CSF)
CEZ	AV0Z20760514 - UT-L (2005-2011)
	AV0Z50390703 - UEM-P (2007-2013)
	AV0Z40500505 - UMCH-V (2005-2011)
Annotation	Chondrocytes (CH) differentiation and proliferation on various scaffolds in vitro was studied theoretically and also experimentally. Theoretical analysis was based on the interaction of the cells with both medium components (MC) including foetal bovine serum (FBS) and growth factors, and the nanofibrous poly(lactic-co-glycolic acid) (PLGA) and poly(2-ethoxyethyl methacrylate) (PEOEMA) scaffolds or tissue culture polystyrene (TCP). The multiplication of activated chondrocytes (CHA), the synthesis of both collagen (COL) and glycosaminoglycans (GAG) on the scaffold (SC), and MC consumption were formulated on the base of chemical kinetic equations, which are set up on the experimental observations.
Workplace	Institute of Thermomechanics
Contact	Marie Kajprová, kajprova@it.cas.cz, Tel.: 266 053 154 ; Jana Lahovská, jaja@it.cas.cz, Tel.: 266 053 823
Year of Publishing	2010

Number of the records: 1