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Dexamethasone and betamethasone administration during pregnancy affects expression and function of 11beta-hydroxysteroid dehydrogenase type 2 in the rat placenta

  1. 1.
    SYSNO ASEP0329480
    Document TypeJ - Journal Article
    R&D Document TypeJournal Article
    Subsidiary JČlánek ve WOS
    TitleDexamethasone and betamethasone administration during pregnancy affects expression and function of 11beta-hydroxysteroid dehydrogenase type 2 in the rat placenta
    TitlePodávání dexametasonu a betametasonu během těhotenství ovlivňuje expresi a funkci 11beta-hydroxysteroiddehydrogenasy v placentě potkana
    Author(s) Vacková, Z. (CZ)
    Vagnerová, Karla (FGU-C) RID, ORCID
    Libra, A. (CZ)
    Mikšík, Ivan (FGU-C) RID, ORCID, SAI
    Pácha, Jiří (FGU-C) RID, ORCID
    Staud, F. (CZ)
    Source TitleReproductive Toxicology. - : Elsevier - ISSN 0890-6238
    Roč. 28, č. 1 (2009), s. 46-51
    Number of pages6 s.
    Languageeng - English
    CountryUS - United States
    Keywordsplacenta ; syntetic glucocorticoids ; 11-betahydroxysteroid dehydrogenasa
    Subject RIVED - Physiology
    R&D ProjectsKJB5011402 GA AV ČR - Academy of Sciences of the Czech Republic (AV ČR)
    CEZAV0Z50110509 - FGU-C (2005-2011)
    UT WOS000267198600007
    DOI10.1016/j.reprotox.2009.02.006
    AnnotationPlacental barrier function mediated by 11-betahydroxysteroid dehydrogenase type 2, an enzyme that protects the fetus against abundance of maternal glucocorticoids, might be considerably impaired by the antenatal therapy with dexamethasone and betamethasone
    WorkplaceInstitute of Physiology
    ContactLucie Trajhanová, lucie.trajhanova@fgu.cas.cz, Tel.: 241 062 400
    Year of Publishing2010
Number of the records: 1  

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