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Nuclear topography of the 1q21 genomic region and MCl-1 protein levels associated with pathophysiology of multiple myeloma
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SYSNO ASEP 0329198 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title Nuclear topography of the 1q21 genomic region and MCl-1 protein levels associated with pathophysiology of multiple myeloma Title Jaderná topografie 1q21 genomické oblasti a množství Mcl-1 proteinu asociované s patofyziologií mnohočetného myelomu Author(s) Legartová, Soňa (BFU-R) ORCID
Krejčí, Jana (BFU-R) RID, ORCID
Harničarová, Andrea (BFU-R) ORCID
Hájek, R. (CZ)
Kozubek, Stanislav (BFU-R) RID
Bártová, Eva (BFU-R) ORCIDSource Title Neoplasma - ISSN 0028-2685
Roč. 56, č. 5 (2009), s. 404-413Number of pages 10 s. Language eng - English Country SK - Slovakia Keywords multiple myeloma ; 1q21 ; DNA-FISH Subject RIV BO - Biophysics R&D Projects LC06027 GA MŠMT - Ministry of Education, Youth and Sports (MEYS) 1QS500040508 GA AV ČR - Academy of Sciences of the Czech Republic (AV ČR) CEZ AV0Z50040507 - BFU-R (2005-2011) AV0Z50040702 - BFU-R (2007-2013) UT WOS 000269333200006 DOI 10.4149/neo_2009_05_404 Annotation Here we suggest that the 1q21 region is an important diagnostic marker of multiple myeloma. Particularly the gene encoding the Mcl-1S protein variant, which can be easily detected by western blots, represent significant diagnostic tool. Workplace Institute of Biophysics Contact Jana Poláková, polakova@ibp.cz, Tel.: 541 517 244 Year of Publishing 2010
Number of the records: 1