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14-3-3 Protein Masks the DNA Binding Interface of Forkhead Transcription Factor FOXO4

SYSNO ASEP	0329194
Document Type	J - Journal Article
R&D Document Type	Journal Article
Subsidiary J	Článek ve WOS
Title	14-3-3 Protein Masks the DNA Binding Interface of Forkhead Transcription Factor FOXO4
Title	14-3-3 protein maskuje DNA vazebné rozhraní forkhead transkripčního faktoru FOXO4
Author(s)	Šilhán, J. (CZ) Vácha, Petr (FGU-C) Strnadová, P. (CZ) Večeř, J. (CZ) Herman, P. (CZ) Šulc, Miroslav (MBU-M)_{RID, ORCID} Teisinger, Jan (FGU-C)_RID Obšilová, Veronika (FGU-C)_{RID, ORCID, SAI} Obšil, Tomáš (FGU-C)_{RID, ORCID}
Source Title	Journal of Biological Chemistry. - : Elsevier - ISSN 0021-9258 Roč. 284, č. 29 (2009), s. 19349-19360
Number of pages	12 s.
Language	eng - English
Country	US - United States
Keywords	14-3-3 protein ; time-resolved fluorescence ; forkhead transcription factor FoxO4
Subject RIV	BO - Biophysics
R&D Projects	IAA501110801 GA AV ČR - Academy of Sciences of the Czech Republic (AV ČR)
	LC554 GA MŠMT - Ministry of Education, Youth and Sports (MEYS)
CEZ	AV0Z50110509 - FGU-C (2005-2011)
	AV0Z50200510 - MBU-M (2005-2011)
UT WOS	000267908300026
DOI	10.1074/jbc.M109.002725
Annotation	Time-resolved fluorescence measurements revealed that the 14-3-3 binding affects fluorescence properties of AEDANS probe attached at four sites within the forkhead domain of FOXO4 that represent important parts of the DNA binding interface. To build a realistic model of the FOXO4-14-3-3 complex, we measured six distances between 14-3-3 and FOXO4 using Förster resonance energy transfer time-resolved fluorescence experiments
Workplace	Institute of Physiology
Contact	Lucie Trajhanová, lucie.trajhanova@fgu.cas.cz, Tel.: 241 062 400
Year of Publishing	2010

Number of the records: 1