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Switching the regioselectivity of direct C-H arylation of 1,3-dimethyluracil

SYSNO ASEP	0328738
Document Type	J - Journal Article
R&D Document Type	Journal Article
Subsidiary J	Článek ve WOS
Title	Switching the regioselectivity of direct C-H arylation of 1,3-dimethyluracil
Author(s)	Čerňová, Miroslava (UOCHB-X) Pohl, Radek (UOCHB-X)_{RID, ORCID} Hocek, Michal (UOCHB-X)_{RID, ORCID}
Number of authors	3
Source Title	European Journal of Organic Chemistry - ISSN 1434-193X -, č. 22 (2009), s. 3698-3701
Number of pages	4 s.
Language	eng - English
Country	DE - Germany
Keywords	pyrimidines ; C-H arylation ; palladium
Subject RIV	CC - Organic Chemistry
R&D Projects	LC06077 GA MŠMT - Ministry of Education, Youth and Sports (MEYS)
CEZ	AV0Z40550506 - UOCHB-X (2005-2011)
UT WOS	000268659900007
DOI	10.1002/ejoc.200900586
Annotation	An interesting dichotomy in regioselectivity and mechanism of direct C-H arylation of 1,3-dimethyluracil was observed. Its Pd-catalyzed reactions with diverse aryl halides in absence of CuI lead preferentially to 5-aryluracils, while the reactions in presence of CuI give 6-aryl derivatives as major products.
Workplace	Institute of Organic Chemistry and Biochemistry
Contact	asep@uochb.cas.cz ; Kateřina Šperková, Tel.: 232 002 584 ; Viktorie Chládková, Tel.: 232 002 434
Year of Publishing	2010

Number of the records: 1