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Labelled compounds as radiopharmaceuticals for radiosynoviorthesis
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SYSNO ASEP 0328173 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title Labelled compounds as radiopharmaceuticals for radiosynoviorthesis Author(s) Melichar, František (UJF-V) RID
Kropáček, Martin (UJF-V) RID
Šrank, Jiří (UJF-V) RID
Beran, Miloš (UJF-V)
Mirzajevová, Marcela (UJF-V)
Zimová, Jana (UJF-V) RID
Eigner-Henke, Kateřina (UJF-V) RID
Forsterová, Michaela (UJF-V)Source Title Journal of Radioanalytical and Nuclear Chemistry. - : Springer - ISSN 0236-5731
Roč. 280, č. 2 (2009), s. 353-358Number of pages 6 s. Action 2nd International Nuclear Chemistry Congress (2nd-INCC) Event date 13.04.2008-17.04.2008 VEvent location Cancun Country MX - Mexico Event type WRD Language eng - English Country HU - Hungary Keywords RHEUMATOID-ARTHRITIS ; RADIATION SYNOVECTOMY ; FOLLOW-UP Subject RIV FR - Pharmacology ; Medidal Chemistry R&D Projects OE08018 GA MŠMT - Ministry of Education, Youth and Sports (MEYS) 2A-1TP1/055 GA MPO - Ministry of Industry and Trade (MPO) 2B06165 GA MŠMT - Ministry of Education, Youth and Sports (MEYS) CEZ AV0Z10480505 - UJF-V (2005-2011) UT WOS 000265714000026 Annotation Radiopharmaceuticals for radiosynoviorthesis are designed as suspension (colloidal) of particles in sterile and pyrogen free form, where radionuclide (active substance) fix on carrier which is form solid particles or gel form. Generally, radionuclide and carrier have to fulfil the request of sterility, chemical purity, non toxicity, non allergen and low cost preparation. In term of the radionuclide purity, beta-emission with sufficient energy for penetration and ablation the synovial tissue and low gamma-radiation is requested. The radionuclide gold-198 in colloidal form was used as radiopharmaceutical for radiosynoviorthesis at first. Presently, beta-emitting radionuclides, which have no or only a minimal gammaemission, are used. Workplace Nuclear Physics Institute Contact Markéta Sommerová, sommerova@ujf.cas.cz, Tel.: 266 173 228 Year of Publishing 2010
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