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Superparamagnetic maghemite nanoparticles from solid-state synthesis – Their functionalization towards peroral MRI contrast agent and magnetic carrier for trypsin immobilization
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SYSNO ASEP 0328087 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title Superparamagnetic maghemite nanoparticles from solid-state synthesis – Their functionalization towards peroral MRI contrast agent and magnetic carrier for trypsin immobilization Title Superparamagnetické maghemitové nanočástice připravené syntézou v pevné fázi – Funkcionalizace k získání perorálního kontrastního činidla pro MRI a magnetického nosiče pro imobilizaci trypsinu Author(s) Kluchová, K. (CZ)
Zbořil, R. (CZ)
Tuček, J. (CZ)
Pečová, M. (CZ)
Zajoncová, L. (CZ)
Šafařík, Ivo (UEK-B) RID, SAI
Mašláň, M. (CZ)
Marková, I. (SK)
Jančík, D. (CZ)
Šebela, M. (CZ)
Bartoňková, H. (CZ)
Bellesi, V. (GR)
Novák, P. (CZ)
Petridis, D. (GR)Source Title Biomaterials. - : Elsevier - ISSN 0142-9612
Roč. 30, - (2009), s. 2855-2863Number of pages 9 s. Language eng - English Country GB - United Kingdom Keywords maghemite ; contrast agent ; composites Subject RIV CE - Biochemistry CEZ AV0Z60870520 - UEK-B (2005-2011) UT WOS 000265328100001 Annotation Nearly monodispersed superparamagnetic maghemite nanoparticles (15–20 nm) were prepared by a one-step thermal decomposition of iron(II) acetate in air at 400 ◦C. The particles can find applicability in medicine and biochemistry. The maghemite particles were dispersed in the bentonite matrix; the resulting nanocomposite represents very effective and cheap oral negative contrast agent for MRI of the gastrointestinal tract. For biochemical applications, the functionalization of maghemite nanoparticles with chitosan was performed. This carrier was used for trypsin immobilization which was subsequently used for MALDI–TOF mass spectrometry. Workplace Global Change Research Institute Contact Nikola Šviková, svikova.n@czechglobe.cz, Tel.: 511 192 268 Year of Publishing 2010
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