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Genome-wide reduction in H3K9 acetylation during human embryonic stem cell differentiation
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SYSNO ASEP 0328047 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title Genome-wide reduction in H3K9 acetylation during human embryonic stem cell differentiation Title Snížení H3K9 acetylace během diferenciace lidských embryonálních kmenových buněk Author(s) Krejčí, Jana (BFU-R) RID, ORCID
Uhlířová, Radka (BFU-R)
Galiová-Šustáčková, Gabriela (BFU-R)
Kozubek, Stanislav (BFU-R) RID
Šmigová, Jana (FGU-C)
Bártová, Eva (BFU-R) ORCIDSource Title Journal of Cellular Physiology. - : Wiley - ISSN 0021-9541
Roč. 219, č. 3 (2009), s. 677-687Number of pages 11 s. Language eng - English Country US - United States Keywords hESC ; H3K9 acetylation ; epigenetics Subject RIV BO - Biophysics R&D Projects LC06027 GA MŠMT - Ministry of Education, Youth and Sports (MEYS) LC535 GA MŠMT - Ministry of Education, Youth and Sports (MEYS) GA204/06/0978 GA ČR - Czech Science Foundation (CSF) CEZ AV0Z50040507 - BFU-R (2005-2011) AV0Z50040702 - BFU-R (2007-2013) AV0Z50110509 - FGU-C (2005-2011) UT WOS 000265547900020 DOI 10.1002/jcp.21714 Annotation The gene density and size of individual chromosomes were strongly correlated with the level of H3K9 acetylation. Our analyses point to chromosomes 11, 12, 17, and 19 as being critical for pluripotency and endoderm-like differentiation of human embryonic stem cells (hESCs). Workplace Institute of Biophysics Contact Jana Poláková, polakova@ibp.cz, Tel.: 541 517 244 Year of Publishing 2010
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