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Energetics, conformation, and recognition of DNA duplexes modified by methylated analogues of [PtCl(dien)]+
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SYSNO ASEP 0327307 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title Energetics, conformation, and recognition of DNA duplexes modified by methylated analogues of [PtCl(dien)]+ Title Energetika, konformace a rozpoznání duplexů DNA modifikovaných methylovanými analogy [PtCl(dien)]+ Author(s) Nováková, Olga (BFU-R) RID, ORCID
Malina, Jaroslav (BFU-R) ORCID
Kašpárková, Jana (BFU-R) RID, ORCID
Halámiková, Anna (BFU-R)
Bernard, Vladan (BFU-R)
Intini, F. (IT)
Natile, G. (IT)
Brabec, Viktor (BFU-R) RID, ORCIDSource Title Chemistry - A European Journal. - : Wiley - ISSN 0947-6539
Roč. 15, č. 25 (2009), s. 6211-6221Number of pages 11 s. Language eng - English Country DE - Germany Keywords platinum complexes ; DNA ; polymerization Subject RIV BO - Biophysics R&D Projects LC06030 GA MŠk - Ministry of Education, Youth and Sports (MEYS) ME08017 GA MŠk - Ministry of Education, Youth and Sports (MEYS) OC08003 GA MŠk - Ministry of Education, Youth and Sports (MEYS) 1QS500040581 GA AV ČR - Academy of Sciences of the Czech Republic (AV ČR) KAN200200651 GA AV ČR - Academy of Sciences of the Czech Republic (AV ČR) IAA400040803 GA AV ČR - Academy of Sciences of the Czech Republic (AV ČR) GA203/06/1239 GA ČR - Czech Science Foundation (CSF) CEZ AV0Z50040507 - BFU-R (2005-2011) AV0Z50040702 - BFU-R (2007-2013) UT WOS 000267501400018 DOI 10.1002/chem.200900388 Annotation Goals of this study, performed in cell-free media, were to determine how the modification of DNA duplexes by methylated analogues of [Pt(NO3)(dien)]+ affects their energetics and how the alterations of this biophysical parameter are reflected by the recognition of these duplexes by DNA polymerases and the DNA repair system. Workplace Institute of Biophysics Contact Jana Poláková, polakova@ibp.cz, Tel.: 541 517 244 Year of Publishing 2010
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