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Carvedilol and adrenergic agonists suppress the lipopolysaccharide-induced NO production in RAW 264.7 macrophages via the adrenergic receptors

SYSNO ASEP	0327031
Document Type	J - Journal Article
R&D Document Type	Journal Article
Subsidiary J	Článek ve WOS
Title	Carvedilol and adrenergic agonists suppress the lipopolysaccharide-induced NO production in RAW 264.7 macrophages via the adrenergic receptors
Title	Carvedilol a adrenergický agonisti inhibují lipopolysaccharidem indukovanou produkci NO u makrofágů RAW 264.7 prostřednictvím adrenergických receptorů
Author(s)	Pekarová, Michaela (BFU-R)_RID Králová, Jana (BFU-R) Kubala, Lukáš (BFU-R)_{RID, ORCID} Číž, Milan (BFU-R)_{RID, ORCID} Papežíková, Ivana (BFU-R) Mačičková, T. (SK) Pečivová, J. (SK) Nosál, R. (SK) Lojek, Antonín (BFU-R)_RID
Source Title	Journal of Physiology and Pharmacology. - : Polskie Towarzystwo Fizjologiczne - ISSN 0867-5910 Roč. 60, č. 1 (2009), s. 143-150
Number of pages	8 s.
Language	eng - English
Country	PL - Poland
Keywords	carvedilol ; adrenergic agonists ; nitric oxide
Subject RIV	BO - Biophysics
R&D Projects	1QS500040507 GA AV ČR - Academy of Sciences of the Czech Republic (AV ČR)
	GA524/08/1753 GA ČR - Czech Science Foundation (CSF)
CEZ	AV0Z50040507 - BFU-R (2005-2011)
	AV0Z50040702 - BFU-R (2007-2013)
UT WOS	000264856700013
Annotation	In this study we demonstrated that adrenergic antagonist carvedilol is able to suppress the production of NO in LPS-stimulated macrophages analogically to adrenaline, noradrenaline and dopamine. Further, we demonstrated that carvedilol and adrenergic agonists participate in the regulation of the NO production in response to LPS via the adrenergic receptors.
Workplace	Institute of Biophysics
Contact	Jana Poláková, polakova@ibp.cz, Tel.: 541 517 244
Year of Publishing	2010

Number of the records: 1