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Acid-base-driven matrix-assisted mass spectrometry for targeted metabolomics
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SYSNO ASEP 0326519 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title Acid-base-driven matrix-assisted mass spectrometry for targeted metabolomics Author(s) Shroff, R. (DE)
Rulíšek, Lubomír (UOCHB-X) RID, ORCID
Doubský, J. (DE)
Svatoš, Aleš (UOCHB-X) ORCID, RIDNumber of authors 4 Source Title Proceedings of the National Academy of Sciences of the United States of America. - : National Academy of Sciences - ISSN 0027-8424
Roč. 106, č. 25 (2009), s. 10092-10096Number of pages 5 s. Language eng - English Country US - United States Keywords clinical diagnostic ; matrix design ; positive/negative ions ; MALDI Subject RIV CF - Physical ; Theoretical Chemistry R&D Projects LC512 GA MŠMT - Ministry of Education, Youth and Sports (MEYS) CEZ AV0Z40550506 - UOCHB-X (2005-2011) UT WOS 000267292200006 DOI 10.1073/pnas.0900914106 Annotation An ionization mode of MAILD, a rational protocol for matrix selection based on Bronsted-Lowry acid-base theory and its application to metabolomics, biological screening/profiling/imaging, and clinical diagnostics is presented. Workplace Institute of Organic Chemistry and Biochemistry Contact asep@uochb.cas.cz ; Kateřina Šperková, Tel.: 232 002 584 ; Viktorie Chládková, Tel.: 232 002 434 Year of Publishing 2010
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