Not EEG abnormalities but epilepsy is associated with autistic regression and mental functioning in childhood autism

Hrdlička, M.; Komárek, V.; Propper, L.; Kulísek, R.; Zumrová, A.; Faladová, L.; Havlovicová, M.; Sedláček, Z.; Blatný, Marek; Urbánek, Tomáš

doi:https://dx.doi.org/10.1007/s00787-004-0353-7

Number of the records: 1

Not EEG abnormalities but epilepsy is associated with autistic regression and mental functioning in childhood autism

1.

SYSNO ASEP	0325596
Document Type	J - Journal Article
R&D Document Type	Journal Article
Subsidiary J	Článek ve WOS
Title	Not EEG abnormalities but epilepsy is associated with autistic regression and mental functioning in childhood autism
Title	Ne abnormity EEG, ale epilepsie má vztah s autistickou regresí a duševním fungováním u dětského autismu
Author(s)	Hrdlička, M. (CZ) Komárek, V. (CZ) Propper, L. (CZ) Kulísek, R. (CZ) Zumrová, A. (CZ) Faladová, L. (CZ) Havlovicová, M. (CZ) Sedláček, Z. (CZ) Blatný, Marek (PSU-E)_{RID, SAI, ORCID} Urbánek, Tomáš (PSU-E)_{RID, ORCID, SAI}
Number of authors	10
Source Title	European Child & Adolescent Psychiatry. - : Springer - ISSN 1018-8827 Roč. 13, č. 4 (2004), s. 209-213
Number of pages	5 s.
Language	eng - English
Country	DE - Germany
Keywords	childhood autism ; epilepsy ; EEG
Subject RIV	AN - Psychology
CEZ	AV0Z7025918 - PSU-E
UT WOS	000224095300002
DOI	10.1007/s00787-004-0353-7
Annotation	The aim of the study was to investigate the potential association of epilepsy and EEG abnormalities with autistic regression and mental retardation. We examined a group of 77 autistic children (61 boys, 16 girls) with an average age of 9.1 ± 5.3 years. Clinical interview, neurological examination focused on the evaluation of epilepsy, IQ testing, and 21-channel EEG (including night sleep EEG recording) were performed. Normal EEGs were observed in 44.4% of the patients, non-epileptiform abnormal EEGs in 17.5%, and abnormal EEGs with epileptiform discharges in 38.1% of the patients. Epilepsy was found in 22.1% of the subjects. A history of regression was reported in 25.8% of the patients, 54.8% of the sample had abnormal development during the first year of life, and 79.7% of the patients were mentally retarded. Autistic regression was significantly more frequent in patients with epilepsy than in non-epileptic patients (p = 0.003). Abnormal development during the first year of life was significantly associated with epileptiform EEG abnormalities (p = 0.014). Epilepsy correlated significantly with mental retardation (p = 0.001).
Workplace	Institute of Psychology
Contact	Štěpánka Halamová, Halamova@praha.psu.cas.cz, Tel.: 222 222 096
Year of Publishing	2009

Number of the records: 1