Number of the records: 1

Copper/ascorbic acid dyad as a catalytic system for selective aerobic oxidation of amines

SYSNO ASEP	0324912
Document Type	J - Journal Article
R&D Document Type	Journal Article
Subsidiary J	Článek ve WOS
Title	Copper/ascorbic acid dyad as a catalytic system for selective aerobic oxidation of amines
Title	Měď/askorbová kyselina jako katalytický systém pro selektivní aerobní oxidaci aminů
Author(s)	Šrogl, Jiří (UOCHB-X) Voltrová, Svatava (UOCHB-X)_{RID, ORCID}
Source Title	Organic Letters. - : American Chemical Society - ISSN 1523-7060 Roč. 11, č. 4 (2009), s. 843-845
Number of pages	3 s.
Language	eng - English
Country	US - United States
Keywords	copper ; ascorbic acid ; oxidative deamination
Subject RIV	CC - Organic Chemistry
CEZ	AV0Z40550506 - UOCHB-X (2005-2011)
UT WOS	000263299000015
DOI	10.1021/0l802715c
Annotation	A new, environmentally benign system based on ascorbic acid (vitamin C)/copper dyad is presented, which facilitates the oxidation of amines to carbonyl compounds. The oxidation utilizes aerobic oxygen as the ultimate electron scavenger, which accepts electrons, in a cascade-like fashion, via a Cu+/Cu++ and ascorbic/ dehydroascorbic acid couple. Dehydroascorbic acid, the oxidation agent, finally oxidizes amine substrates in a selective fashion after forming a Schiff base intermediate. The selectivity as well as generality of the method is demonstrated on various substrates.
Workplace	Institute of Organic Chemistry and Biochemistry
Contact	asep@uochb.cas.cz ; Kateřina Šperková, Tel.: 232 002 584 ; Viktorie Chládková, Tel.: 232 002 434
Year of Publishing	2009

Number of the records: 1