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Two aspartic proteinases secreted by the pathogenic yeast Candida parapsilosis differ in expression pattern and catalytic properties

SYSNO ASEP	0324742
Document Type	J - Journal Article
R&D Document Type	Journal Article
Subsidiary J	Článek ve WOS
Title	Two aspartic proteinases secreted by the pathogenic yeast Candida parapsilosis differ in expression pattern and catalytic properties
Title	Dvě aspartátové proteázy sekretované patogenní kvasinkou Candida parapsilosis se liší způsobem exprese i katalytickými vlastnostmi
Author(s)	Hrušková-Heidingsfeldová, Olga (UOCHB-X)_{RID, ORCID} Dostál, Jiří (UOCHB-X)_{RID, ORCID} Majer, F. (CZ) Havlíková, J. (CZ) Hradilek, Martin (UOCHB-X)_ORCID Pichová, Iva (UOCHB-X)_{RID, ORCID}
Number of authors	6
Source Title	Biological Chemistry. - : Walter de Gruyter - ISSN 1431-6730 Roč. 390, č. 3 (2009), s. 259-268
Number of pages	10 s.
Language	eng - English
Country	DE - Germany
Keywords	aspartic protease ; Candida parapsilosis
Subject RIV	CE - Biochemistry
R&D Projects	GA203/05/0038 GA ČR - Czech Science Foundation (CSF)
	LC531 GA MŠMT - Ministry of Education, Youth and Sports (MEYS)
CEZ	AV0Z40550506 - UOCHB-X (2005-2011)
UT WOS	000264921500007
DOI	10.1515/BC.2009.034
Annotation	Protease Sapp1p secreted by pathogenic yeast Candida parapsilosis has a higher catalytic activity than the isoenzyme Sapp2p. The gene SAPP2 is transcribed constitutively, while SAPP1 is inducible, it is transcribed only in presence of exogenous protein as a sole source of nitrogen.
Workplace	Institute of Organic Chemistry and Biochemistry
Contact	asep@uochb.cas.cz ; Kateřina Šperková, Tel.: 232 002 584 ; Viktorie Chládková, Tel.: 232 002 434
Year of Publishing	2009

Number of the records: 1