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Development of the light sensitivity of the clock genes Period1 and Period2, and immediate-early gene c-fos within the rat suprachiasmatic nucleus

SYSNO ASEP	0323450
Document Type	J - Journal Article
R&D Document Type	Journal Article
Subsidiary J	Článek ve WOS
Title	Development of the light sensitivity of the clock genes Period1 and Period2, and immediate-early gene c-fos within the rat suprachiasmatic nucleus
Title	Vývoj citlivosti ke světlu hodinových genů Period1 a Period2 a časného raného genu c-fos v suprachiasmatických jádrech laboratorního potkana
Author(s)	Matějů, Kristýna (FGU-C) Bendová, Zdena (FGU-C) El-Hennamy, Rehab (FGU-C) Sládek, Martin (FGU-C)_{RID, ORCID, SAI} Sosniyenko, Serhiy (FGU-C) Sumová, Alena (FGU-C)_{RID, ORCID}
Source Title	European Journal of Neuroscience - ISSN 0953-816X Roč. 29, č. 3 (2009), s. 490-501
Number of pages	12 s.
Language	eng - English
Country	GB - United Kingdom
Keywords	circadian clock ; ontogenesis ; photic entrainment
Subject RIV	FH - Neurology
R&D Projects	GA309/08/0503 GA ČR - Czech Science Foundation (CSF)
	LC554 GA MŠMT - Ministry of Education, Youth and Sports (MEYS)
CEZ	AV0Z50110509 - FGU-C (2005-2011)
UT WOS	000262951200007
DOI	10.1111/j.1460-9568.2009.06609.x
Annotation	Expression of Per1 and c-fos was light responsive from the first postnatal day (P1), and the responses began to be gated by the circadian clock at P3 and P10, respectively. Expression of Per2 was only slightly light responsive at P3, and the response was not fully gated until P5. These data demonstrate that the light sensitivity of the circadian clock develops gradually during postnatal ontogenesis before the circadian clock starts to control the response. The photoinduction of the clock gene Per2 develops later than that of Per1
Workplace	Institute of Physiology
Contact	Lucie Trajhanová, lucie.trajhanova@fgu.cas.cz, Tel.: 241 062 400
Year of Publishing	2009

Number of the records: 1