Number of the records: 1

Molecular dynamics suggest multifunctionality of an adenine imino group in acid-base catalysis of the hairpin ribozyme

SYSNO ASEP	0323266
Document Type	J - Journal Article
R&D Document Type	Journal Article
Subsidiary J	Článek ve WOS
Title	Molecular dynamics suggest multifunctionality of an adenine imino group in acid-base catalysis of the hairpin ribozyme
Title	Molekulová dynamika ukazuje na multifunkčnost imino skupiny adeninu v katalýze kyselé báze hairpin ribozymu
Author(s)	Ditzler, M.A. (US) Šponer, Jiří (BFU-R)_{RID, ORCID} Walter, N.G. (US)
Source Title	RNA. - : Cold Spring Harbor Laboratory Press - ISSN 1355-8382 Roč. 15, č. 4 (2009), s. 560-575
Number of pages	16 s.
Language	eng - English
Country	US - United States
Keywords	molecular dynamics ; ribozyme ; catalytic mechanism
Subject RIV	BO - Biophysics
R&D Projects	IAA400040802 GA AV ČR - Academy of Sciences of the Czech Republic (AV ČR)
CEZ	AV0Z50040507 - BFU-R (2005-2011)
	AV0Z50040702 - BFU-R (2007-2013)
UT WOS	000264280100006
DOI	10.1261/rna.1416709
Annotation	Molecular dynamics study of the catalytic mechanism of hairpin ribozyme. The calculations were supplemented by electrophoretic mobility shift essay. Main attention of this study was paid to A38 base and hydration of the catalytic site as well.
Workplace	Institute of Biophysics
Contact	Jana Poláková, polakova@ibp.cz, Tel.: 541 517 244
Year of Publishing	2009

Number of the records: 1