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Norsesquiterpene hydrocarbon, chemical composition and antimicrobial activity of Rhaponticum carthamoides root essential oil

SYSNO ASEP	0322938
Document Type	J - Journal Article
R&D Document Type	Journal Article
Subsidiary J	Článek ve WOS
Title	Norsesquiterpene hydrocarbon, chemical composition and antimicrobial activity of Rhaponticum carthamoides root essential oil
Title	Norseskviterpen, chemické složení a antimikrobiální aktivita silice z kořenů Rhaponticum carthamoides
Author(s)	Havlík, J. (CZ) Buděšínský, Miloš (UOCHB-X)_{RID, ORCID} Klouček, P. (CZ) Kokoška, L. (CZ) Valterová, Irena (UOCHB-X)_{RID, ORCID} Vašíčková, Soňa (UOCHB-X) Zelený, V. (CZ)
Number of authors	7
Source Title	Phytochemistry. - : Elsevier - ISSN 0031-9422 Roč. 70, č. 3 (2009), s. 414-418
Number of pages	5 s.
Language	eng - English
Country	GB - United Kingdom
Keywords	13-norcypera-1(5),11(12)-diene ; cyperene ; antimicrobial activity
Subject RIV	CC - Organic Chemistry
CEZ	AV0Z40550506 - UOCHB-X (2005-2011)
UT WOS	000265339400012
DOI	10.1016/j.phytochem.2008.12.018
Annotation	A detailed analysis of Rhaponticum carthamoides (Willd.) Iljin root essential oil was carried out by GC, GC–MS and GC–FTIR techniques. In total, 30 components were identified. A new norsesquiterpene 13-norcypera-1(5),11(12)-diene (22.6%), followed by aplotaxene (21.2%) and cyperene (17.9%), were isolated and their structures confirmed by 1D and 2D-NMR spectra (COSY, ROESY, HSQC, HMBC and INADEQUATE). The oil exhibited antimicrobial activity against 5 of 9 strains of bacteria. Minimum inhibitory concentrations ranged between 32 and 256 µg/ml.
Workplace	Institute of Organic Chemistry and Biochemistry
Contact	asep@uochb.cas.cz ; Kateřina Šperková, Tel.: 232 002 584 ; Viktorie Chládková, Tel.: 232 002 434
Year of Publishing	2009

Number of the records: 1