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New binary thermoresponsive polymeric system for local chemoradiotherapy

SYSNO ASEP	0319379
Document Type	J - Journal Article
R&D Document Type	Journal Article
Subsidiary J	Článek ve WOS
Title	New binary thermoresponsive polymeric system for local chemoradiotherapy
Title	Nový termoresponsivní polymerní systém pro lokální chemoradioterapii
Author(s)	Hrubý, Martin (UMCH-V)_{RID, ORCID} Kučka, Jan (UJF-V)_RID Macková, Hana (UMCH-V)_RID Koňák, Čestmír (UMCH-V)_RID Větřík, M. (CZ) Kozempel, Ján (UJF-V) Lebeda, Ondřej (UJF-V)_{RID, ORCID, SAI}
Source Title	Journal of Applied Polymer Science. - : Wiley - ISSN 0021-8995 Roč. 111, č. 5 (2009), s. 2220-2228
Number of pages	9 s.
Language	eng - English
Country	US - United States
Keywords	copolymerization ; drug delivery systems ; functionalization of polymers
Subject RIV	CD - Macromolecular Chemistry
R&D Projects	IAA400480616 GA AV ČR - Academy of Sciences of the Czech Republic (AV ČR)
	KAN200200651 GA AV ČR - Academy of Sciences of the Czech Republic (AV ČR)
	GESON/06/E005 GA ČR - Czech Science Foundation (CSF)
CEZ	AV0Z40500505 - UMCH-V (2005-2011)
	AV0Z10480505 - UJF-V (2005-2011)
UT WOS	000262322900007
DOI	doi:10.1002/app.29237
Annotation	A new polymeric drug delivery system designed for combined local chemoradiotherapy using injectable thermoresponsive polymer bearing the radionuclide and the hydrophobic moiety doxorubicin was synthesized and characterized. Doxorubicin is bound to the polymer carrier by a hydrolytically labile N-glycosylamine bond.
Workplace	Institute of Macromolecular Chemistry
Contact	Eva Čechová, cechova@imc.cas.cz ; Tel.: 296 809 358
Year of Publishing	2009

Number of the records: 1