Number of the records: 1

Cryptosporidia: Epicellular parasites embraced by the host cell membrane

SYSNO ASEP	0319176
Document Type	J - Journal Article
R&D Document Type	Journal Article
Subsidiary J	Článek ve WOS
Title	Cryptosporidia: Epicellular parasites embraced by the host cell membrane
Title	Kryptosporidie: epicelulární parazité v objetí membrány hostitelské buňky
Author(s)	Valigurová, A. (CZ) Jirků, Miloslav (BC-A)_{RID, ORCID} Koudela, Břetislav (BC-A)_ORCID Gelnar, M. (CZ) Modrý, David (BC-A)_{RID, ORCID} Šlapeta, J. (AU)
Number of authors	6
Source Title	International Journal for Parasitology. - : Elsevier - ISSN 0020-7519 Roč. 38, 8/9 (2008), s. 913-922
Number of pages	10 s.
Language	eng - English
Country	AU - Australia
Keywords	Cryptosporidium ; host cell invasion ; epicellular ; parasitophorous sac ; ultrastructure
Subject RIV	GJ - Animal Vermins ; Diseases, Veterinary Medicine
R&D Projects	GD524/03/H133 GA ČR - Czech Science Foundation (CSF)
	GA524/05/0992 GA ČR - Czech Science Foundation (CSF)
	LC522 GA MŠMT - Ministry of Education, Youth and Sports (MEYS)
CEZ	AV0Z60220518 - PAU-O, BC-A (2005-2011)
UT WOS	000257001300004
DOI	10.1016/j.ijpara.2007.11.003
Annotation	The ultrastructure of two gastric cryptosporidia, Cryptosporidium muris from experimentally infected rodents (Mastomys natalensis) and Cryptosporidium sp. 'toad' from naturally infected toads (Duttaphrynus melanostictus), was studied. Presented observations allowed us to map ultrastructural aspects of the cryptosporidian invasion process and the origin of a parasitophorous sac. Invading parasites attach to the host cell, followed by gradual envelopment, with the host's cell membrane folds, eventually forming the parasitophorous sac. Cryptosporidian developmental stages remain epicellular during the entire life cycle. The parasite development is illustrated in detail using high resolution field emission scanning electron microscopy. This provides a new insight into the ultrastructural detail of host-parasite interactions.
Workplace	Biology Centre (since 2006)
Contact	Dana Hypšová, eje@eje.cz, Tel.: 387 775 214
Year of Publishing	2009

Number of the records: 1