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Plasma membrane microdomains regulate turnover of transport proteins in yeast

SYSNO ASEP	0318765
Document Type	J - Journal Article
R&D Document Type	Journal Article
Subsidiary J	Článek ve WOS
Title	Plasma membrane microdomains regulate turnover of transport proteins in yeast
Title	Mikrodomény v plasmatické membráně regulují turnover transportních proteinů v kvasinkách
Author(s)	Grossmann, G. (DE) Malínský, Jan (UEM-P)_{RID, ORCID} Stahlschmidt, W. (DE) Loibl, M. (DE) Weig-Meckl, I. (DE) Frommer, W.B. (CA) Opekarová, Miroslava (MBU-M) Tanner, W. (DE)
Source Title	Journal of Cell Biology. - : Rockefeller University Press - ISSN 0021-9525 Roč. 183, č. 6 (2008), s. 1075-1088
Number of pages	14 s.
Language	eng - English
Country	US - United States
Keywords	Lithium acetate ; Membrane compartment of Can1 ; Monomeric red fluorescent protein
Subject RIV	EA - Cell Biology
R&D Projects	GA204/06/0009 GA ČR - Czech Science Foundation (CSF)
	GA204/07/0133 GA ČR - Czech Science Foundation (CSF)
	GC204/08/J024 GA ČR - Czech Science Foundation (CSF)
CEZ	AV0Z50390703 - UEM-P (2007-2013)
	AV0Z50200510 - MBU-M (2005-2011)
UT WOS	000261783100013
DOI	10.1083/jcb.200806035
Annotation	We show that twenty-one proteins cluster either within or associated with the ergosterol-rich membrane compartment C (MCC). In a screen we identified 28 genes affecting MCC appearance. Our data suggest that their release from MCC makes the proteins accessible to the endocytic machinery. Thus, MCC represents a protective area within the plasma membrane to control turnover of transport proteins.
Workplace	Institute of Experimental Medicine
Contact	Lenka Koželská, lenka.kozelska@iem.cas.cz, Tel.: 241 062 218, 296 442 218
Year of Publishing	2009

Number of the records: 1