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Nanometer size wear debris generated from ultra high molecular weight polyethylene in vivo
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SYSNO ASEP 0318216 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title Nanometer size wear debris generated from ultra high molecular weight polyethylene in vivo Title Nanometrové otěrové částice ultra vysokomolekulárního polyethylenu generované in vivo Author(s) Lapčíková, Monika (UMCH-V) RID
Šlouf, Miroslav (UMCH-V) RID, ORCID
Dybal, Jiří (UMCH-V) RID, ORCID
Zolotarevova, E. (CZ)
Entlicher, G. (CZ)
Pokorný, D. (CZ)
Gallo, J. (CZ)
Sosna, A. (CZ)Source Title Wear. - : Elsevier - ISSN 0043-1648
Roč. 266, 1-2 (2009), s. 349-355Number of pages 7 s. Language eng - English Country CH - Switzerland Keywords ultra high molecular weight polyethylene ; nanometer size wear debris ; morphology of wear particles Subject RIV CD - Macromolecular Chemistry R&D Projects 2B06096 GA MŠMT - Ministry of Education, Youth and Sports (MEYS) CEZ AV0Z40500505 - UMCH-V (2005-2011) UT WOS 000261538800041 DOI 10.1016/j.wear.2008.06.005 Annotation This study brings the first evidence that nanosized wear particles with sizes below 0.05 µm are produced in vivo. UHMWPE wear nanoparticles were revealed by high-resolution, field emission gun scanning electron microscopy (FEGSEM) in the periprosthetic tissues of two different patients. Purity of the isolated wear nanoparticles was confirmed by energy-dispersive analysis of X-rays (EDS) and infrared spectroscopy (IR). Morphology of wear nanoparticles was determined by image analysis of FEGSEM micrographs. The average equivalent diameters of wear particles in the first and the second patient were 18.5 and 21.2 nm, respectively. Workplace Institute of Macromolecular Chemistry Contact Eva Čechová, cechova@imc.cas.cz ; Tel.: 296 809 358 Year of Publishing 2009
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