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Controlled preparation of thin fibrin films immobilized at solid surfaces
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SYSNO ASEP 0318203 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title Controlled preparation of thin fibrin films immobilized at solid surfaces Title Kontrolovaný způsob přípravy tenkých fibrinových sítí imobilizovaných na povrchu Author(s) Riedel, Tomáš (UMCH-V) RID, ORCID
Brynda, Eduard (UMCH-V) RID
Dyr, J. E. (CZ)
Houska, Milan (UMCH-V) RIDSource Title Journal of Biomedical Materials Research. Part A. - : Wiley - ISSN 1549-3296
88A, č. 2 (2009), s. 437-447Number of pages 11 s. Language eng - English Country US - United States Keywords fibrin gel coatings ; thin films ; tissue engineering Subject RIV CE - Biochemistry R&D Projects IAA400500507 GA AV ČR - Academy of Sciences of the Czech Republic (AV ČR) CEZ AV0Z40500505 - UMCH-V (2005-2011) UT WOS 000262228300018 DOI 10.1002/jbm.a.31755 Annotation A technique for coating surfaces with attached fibrin structures without the formation of fibrin gel in bulk solution was developed. It is based on the catalytic effect of the surface-bound thrombin on fibrinogen stabilized with inhibitor which inhibits thrombin in solution but not the thrombin on the surface. Such an inhibitor is antithrombin, the effect of which may be enhanced with heparin. Workplace Institute of Macromolecular Chemistry Contact Eva Čechová, cechova@imc.cas.cz ; Tel.: 296 809 358 Year of Publishing 2009
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