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Cytokine response to Escherichia coli in gnotobiotic pigs
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SYSNO ASEP 0317666 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title Cytokine response to Escherichia coli in gnotobiotic pigs Title Cytokinová odpověď na Escherichia coli u gnotobiotických prasat Author(s) Šplíchal, Igor (MBU-M) RID
Šplíchalová, Alla (MBU-M) RID, ORCID
Trebichavský, Ilja (MBU-M)Source Title Folia Microbiologica. - : Springer - ISSN 0015-5632
Roč. 53, č. 2 (2008), s. 161-164Number of pages 4 s. Language eng - English Country CZ - Czech Republic Keywords germ-free pigs ; escherichia coli ; cytokine response Subject RIV EE - Microbiology, Virology R&D Projects GA523/05/0249 GA ČR - Czech Science Foundation (CSF) CEZ AV0Z50200510 - MBU-M (2005-2011) UT WOS 000255837600010 DOI - Annotation One-week-old-germ-free pigs were inoculated with 108 CFU of E.coli bacteria-either commensal O86 strain or virulent 055 strain for 1 d. Bacteria were counted in the small intestine, mesenteric lymph nodes, blood and lungs. The O55 strain reached higher levels in circulation and lungs. IL-8, IL-10 and TNF-alpha concentrations were determined by ELISA in plasma and intestinal washes . No difference in cytokine levels was found between control germ-free pigs and their counterparts associated with commensal O86 strain in spite of its high concentration in the gut and circulation Workplace Institute of Microbiology Contact Eliška Spurná, eliska.spurna@biomed.cas.cz, Tel.: 241 062 231 Year of Publishing 2009
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