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Age-related changes in GAD levels in the central auditory system of the rat
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SYSNO ASEP 0316696 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title Age-related changes in GAD levels in the central auditory system of the rat Title Změny v obsahu GAD v centrálním sluchovém systému v závislosti na věku potkana Author(s) Burianová, Jana (UEM-P)
Ouda, Ladislav (UEM-P) RID
Profant, Oliver (UEM-P)
Syka, Josef (UEM-P) RIDSource Title Experimental Gerontology. - : Elsevier - ISSN 0531-5565
Roč. 44, č. 3 (2009), s. 161-169Number of pages 8 s. Language eng - English Country US - United States Keywords Inferior colliculus ; Auditory cortex ; Rat Subject RIV FH - Neurology R&D Projects GA309/07/1336 GA ČR - Czech Science Foundation (CSF) NR8113 GA MZd - Ministry of Health (MZ) LC554 GA MŠMT - Ministry of Education, Youth and Sports (MEYS) CEZ AV0Z50390512 - UEM-P (2005-2011) UT WOS 000264045300003 DOI doi:10.1016/j.exger.2008.09.012 Annotation Aging is associated with a decrease in the numbers of GAD65- and 67-immunoreactive neurons and the optical density of their somas in both the IC and AC, in addition, western blot analysis revealed a pronounced age-related decline in the levels of GAD65 and 67 proteins in both the IC and AC. For comparison, in the visual cortex the decrease in both proteins was less pronounced than in the IC and AC. Workplace Institute of Experimental Medicine Contact Lenka Koželská, lenka.kozelska@iem.cas.cz, Tel.: 241 062 218, 296 442 218 Year of Publishing 2009
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