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Oxidative DNA damage in bone marrow cells of patients with low-risk myelodysplastic syndrome

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    SYSNO ASEP0310043
    Document TypeJ - Journal Article
    R&D Document TypeJournal Article
    Subsidiary JČlánek ve WOS
    TitleOxidative DNA damage in bone marrow cells of patients with low-risk myelodysplastic syndrome
    TitleOxidační poškození DNA v buňkách kostní dřeně pacientů s myelodysplastickým syndromem
    Author(s) Novotná, Božena (UEM-P)
    Bagryantseva, Yana (UEM-P)
    Šišková, M. (CZ)
    Neuwirtová, R. (CZ)
    Source TitleLeukemia Research. - : Elsevier - ISSN 0145-2126
    Roč. 33, č. 2 (2009), s. 340-343
    Number of pages4 s.
    Languageeng - English
    CountryGB - United Kingdom
    KeywordsMyelodysplastic syndrome ; Refractory anemia ; Oxidative DNA damage
    Subject RIVEB - Genetics ; Molecular Biology
    R&D ProjectsNR8265 GA MZd - Ministry of Health (MZ)
    CEZAV0Z50390512 - UEM-P (2005-2011)
    UT WOS000262576400023
    DOI10.1016/j.leukres.2008.07.005
    AnnotationCompared to controls, MDS patients exhibit a significant increase of oxidative damage to DNA in both glycophorin A positive and glycophorin A negative bone marrow fraction which could contribute to genomic instability and disease progression.
    WorkplaceInstitute of Experimental Medicine
    ContactLenka Koželská, lenka.kozelska@iem.cas.cz, Tel.: 241 062 218, 296 442 218
    Year of Publishing2009
Number of the records: 1