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New 2-alkynyl derivatives of the acyclic nucleoside 9-(2,3-dihydroxypropyl)adenine and their 6-guanidinopurine counterparts as potential effectors of adenosine receptors
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SYSNO ASEP 0194994 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Ostatní články Title New 2-alkynyl derivatives of the acyclic nucleoside 9-(2,3-dihydroxypropyl)adenine and their 6-guanidinopurine counterparts as potential effectors of adenosine receptors Author(s) Česnek, Michal (UOCHB-X) RID, ORCID
Holý, Antonín (UOCHB-X)
Masojídková, Milena (UOCHB-X)Source Title Collection of Czechoslovak Chemical Communications. - : Ústav organické chemie a biochemie AV ČR, v. v. i. - ISSN 0010-0765
Roč. 68, č. 11 (2003), s. 2201-2218Number of pages 18 s. Language eng - English Country CZ - Czech Republic Keywords adenosine receptors ; alkynes ; purines Subject RIV CC - Organic Chemistry R&D Projects IBS4055109 GA AV ČR - Academy of Sciences of the Czech Republic (AV ČR) OC D13.20 GA MŠMT - Ministry of Education, Youth and Sports (MEYS) CEZ AV0Z4055905 - UOCHB-X Annotation A series of the new 2-alkynyl derivatives of the acyclic nucleoside 9-(2,3-dihydroxypropyl)-adenine and their 6-guanidinopurine analogues were prepared by the Sonogashira coupling. The effect of the prepared compounds on A1 and A2A receptors was examined. Workplace Institute of Organic Chemistry and Biochemistry Contact asep@uochb.cas.cz ; Kateřina Šperková, Tel.: 232 002 584 ; Viktorie Chládková, Tel.: 232 002 434 Year of Publishing 2004
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