Soluble form of carbonic anhydrase IX (CA IX) in the serum and urine of renal carcinoma patients
1.
SYSNO ASEP
0191607
Document Type
J - Journal Article
R&D Document Type
Journal Article
Subsidiary J
Ostatní články
Title
Soluble form of carbonic anhydrase IX (CA IX) in the serum and urine of renal carcinoma patients
Author(s)
Závada, Jan (UMG-J) Závadová, Zuzana (UMG-J) Zaťovičová, M. (SK) Hyršl, L. (CZ) Kawaciuk, I. (CZ)
Source Title
British Journal of Cancer. - : Springer
- ISSN 0007-0920
Roč. 89, - (2003), s. 1067-1071
Number of pages
5 s.
Language
eng - English
Country
GB - United Kingdom
Keywords
carbonic anhydrase IX ; tumor antigens ; cancer diagnostics
Subject RIV
EC - Immunology
R&D Projects
GA301/99/0356 GA ČR - Czech Science Foundation (CSF)
CEZ
AV0Z5052915 - UMG-J
Annotation
Tumor-associated protein CA IX has two major forms. One is a cell-associated, transmembrane protein of 54/58 kDa, expressed in gastric mucosa and in several types of cancer. The other is a soluble protein s-CA IX (50/54 kDa) released into body fluids. Conceivably, s-CA IX might serve as a marker antigen for monitoring certain groups of cancer patients after surgery and/or chemotherapy.
