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Local IFN-gamma therapy of HPV16-associated tumours
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SYSNO ASEP 0191581 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Ostatní články Title Local IFN-gamma therapy of HPV16-associated tumours Author(s) Mikyšková, Romana (UMG-J) RID
Bieblová, Jana (UMG-J)
Šímová, Jana (UMG-J) RID
Indrová, Marie (UMG-J) RID
Jandlová, Táňa (UMG-J)
Vonka, V. (CZ)
Šmahel, M. (CZ)
Bubeník, Jan (UMG-J)
Mendoza, Luis (UMG-J)Source Title Folia Biologica. - : Univerzita Karlova v Praze - ISSN 0015-5500
Roč. 49, č. 1 (2003), s. 26-32Number of pages 7 s. Language eng - English Country CZ - Czech Republic Keywords MHC class I ; IFN-gamma ; HPV16 Subject RIV FD - Oncology ; Hematology R&D Projects NC7148 GA MZd - Ministry of Health (MZ) NC5900 GA MZd - Ministry of Health (MZ) GA301/01/0985 GA ČR - Czech Science Foundation (CSF) CEZ AV0Z5052915 - UMG-J Annotation The paper examines whether peritumoral administration of IFN-gamma can inhibit growth of HPV16-associated, MHC class I- MK16 tumour transplanted in syngeneic mice. Treatment of tumour transplants with IFN-gamma was efficient until the tumours reached a palpable size. Treatment of surgically induced minimal residual tumour disease was moderate, reproducible, but statistically insignificant. Workplace Institute of Molecular Genetics Contact Nikol Škňouřilová, nikol.sknourilova@img.cas.cz, Tel.: 241 063 217 Year of Publishing 2004
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