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TRAIL (Apo2L) supresses growth of primary human leukemia and myelodysplasia progenitors

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    SYSNO ASEP0191506
    Document TypeJ - Journal Article
    R&D Document TypeJournal Article
    Subsidiary JOstatní články
    TitleTRAIL (Apo2L) supresses growth of primary human leukemia and myelodysplasia progenitors
    Author(s) Plášilová, M. (CZ)
    Živná, J. (CZ)
    Jelínek, J. (CZ)
    Neuwirtová, R. (CZ)
    Čermák, J. (CZ)
    Nečas, E. (CZ)
    Anděra, Ladislav (UMG-J) RID
    Stopka, T. (CZ)
    Source TitleLeukemia. - : Springer - ISSN 0887-6924
    Roč. 16, č. 1 (2002), s. 67-73
    Number of pages7 s.
    Languageeng - English
    CountryUS - United States
    KeywordsTRAIL ; leukemia ; myelodysplasia
    Subject RIVEB - Genetics ; Molecular Biology
    R&D ProjectsIAA5052001 GA AV ČR - Academy of Sciences of the Czech Republic (AV ČR)
    GA301/99/0350 GA ČR - Czech Science Foundation (CSF)
    AnnotationRecombinant His-TRAIL reduced the number of myeloid colonies from patients with myeloid leukemia and myelodysplstic syndromes. TRAIL did not affect normal human hematopoiesis but suppressed the growth of early primary leukemia progenitors.
    WorkplaceInstitute of Molecular Genetics
    ContactNikol Škňouřilová, nikol.sknourilova@img.cas.cz, Tel.: 241 063 217
    Year of Publishing2003

Number of the records: 1  

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