TFIIH Plays an Esswntial Role in RNA Polymerase I Transcription
1.
SYSNO ASEP
0173582
Document Type
J - Journal Article
R&D Document Type
Journal Article
Subsidiary J
Ostatní články
Title
TFIIH Plays an Esswntial Role in RNA Polymerase I Transcription
Author(s)
Iben, S. (DE) Tschochner, H. (DE) Bier, M. (DE) Hoogstraten, D. (NL) Hozák, Pavel (UEM-P) Egly, J. M. (FR) Grummt, I. (DE)
Source Title
Cell. - : Cell Press
- ISSN 0092-8674
Roč. 109, č. 3 (2002), s. 297-306
Number of pages
10 s.
Language
eng - English
Country
US - United States
Keywords
mouse ; yeast
Subject RIV
EA - Cell Biology
R&D Projects
IAA5039202 GA AV ČR - Academy of Sciences of the Czech Republic (AV ČR)
CEZ
AV0Z5039906 - UEM-P
Annotation
TFIIH is a multisubunit protein complex that plays an essential role in nucleotide excision repair and transcription of protein-coding genes. Here, we report that TFIIH is also required for ribosomal RNA synthesis in vivo and in vitro. The results provide a molecular link between RNA polymerase I transcription and transcription-coupled repair of active ribosomal RNA genes.
