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Chemiluminescence at the Turn of the Millennium. An indispensible Tool in modern Chemistry, Biochemistry and Medicine
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SYSNO ASEP 0126503 Document Type M - Monograph Chapter R&D Document Type Monograph Chapter Title Oxidative Stress in Patients with Regular Hemodialysis Measured by Chemiluminescence Author(s) Kubala, Lukáš (BFU-R) RID, ORCID
Číž, Milan (BFU-R) RID, ORCID
Lojek, Antonín (BFU-R) RID
Studeník, P. (CZ)
Černý, J. (CZ)
Soška, V. (CZ)Source Title Chemiluminescence at the Turn of the Millennium. An indispensible Tool in modern Chemistry, Biochemistry and Medicine / Albrecht S. ; Zimmermann T. ; Brandl H.. - Dresden : SCHWEDAWERBEDRUCK GmbH, Druckerei and Verlag, 2001 - ISBN 3-9807853-0-0 Pages s. 264-269 Number of pages 6 s. Language eng - English Country DE - Germany Keywords oxidative stress ; chemiluminescence Subject RIV BO - Biophysics R&D Projects IBS5004009 GA AV ČR - Academy of Sciences of the Czech Republic (AV ČR) NA4796 GA MZd - Ministry of Health (MZ) CEZ AV0Z5004920 - BFU-R Annotation The aim of the study was to examine the phagocyte-derived production of reactive oxygen species, the expression of surface receptors and the total peroxyl radical-trapping antioxidant potential of plasma in patients with regular hemodialysis. The decline of reactive oxygen species generation and the increased expression of CD11b both on neutrophils and monocytes was found after hemodialysis. The antioxidant potential of plasma before hemodialysis treatment was higher when compared with healthy controls. However, it decreased significantly even below this of healthy controls after the treatment. In conclusion, chemiluminiscence can be a very important tool for the assessment of various parameters of oxidative stress. Decreased peroxyl radical-trapping antioxidant potential of plasma indicates insufficient antioxidant defence in patients with chronic renal failure Workplace Institute of Biophysics Contact Jana Poláková, polakova@ibp.cz, Tel.: 541 517 244 Year of Publishing 2002
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