Number of the records: 1
Bio-compatibility of ion beam-modified and RGD-grafted polyethylene
- 1.
SYSNO ASEP 0105594 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Ostatní články Title Bio-compatibility of ion beam-modified and RGD-grafted polyethylene Title Biokompatibilita polyethylenu modifikovaného ozářením ionty a roubováním RGD Author(s) Ročková-Hlaváčková, K. (CZ)
Švorčík, V. (CZ)
Bačáková, L. (CZ)
Dvořánková, B. (CZ)
Heitz, J. (CZ)
Hnatowicz, Vladimír (UJF-V) RIDSource Title Nuclear Instruments & Methods in Physics Research Section B. - : Elsevier - ISSN 0168-583X
Roč. 225, č. 3 (2004), s. 275-282Number of pages 7 s. Language eng - English Country NL - Netherlands Keywords modified polyethylene ; ion beam ; RGD grafting Subject RIV BG - Nuclear, Atomic and Molecular Physics, Colliders R&D Projects IAA5011301 GA AV ČR - Academy of Sciences of the Czech Republic (AV ČR) CEZ AV0Z1048901 - UJF-V Annotation Polyethylene (PE) was implanted with 15 keV Ar+ and Kr+ ions to the fluences from 3 x 10(12)-1 x 10(15) cm(-2) and subsequently grafted with amino acid sequence Arg-Gly-Asp (RGD), i.e. a minimum adhesion motif recognized by integrin receptors on cells. The structural changes of PE were studied using goniometric technique, UV-VIS, LIF spectroscopy and by measuring specimen electrical resistance. The adhesion and proliferation of mouse embryonic fibroblasts 3T3 on the modified PE were studied under in vitro conditions. Addition of RGD sequence onto double bonds created by the ion irradiation on polymeric chain was observed. The adhesion and proliferation of the 3T3 cells is increased by ion implantation and additionally also by RGD grafting Workplace Nuclear Physics Institute Contact Markéta Sommerová, sommerova@ujf.cas.cz, Tel.: 266 173 228 Year of Publishing 2005
Number of the records: 1