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Bio-compatibility of ion beam-modified and RGD-grafted polyethylene
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SYSNO ASEP 0104194 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Ostatní články Title Bio-compatibility of ion beam-modified and RGD-grafted polyethylene Title Biokompatibilita polyetylénu modifikovaného ozářením ionty a roubováním aminokyselinovou sekvencí RGD Author(s) Ročková-Hlaváčková, K. (CZ)
Švorčík, V. (CZ)
Bačáková, Lucie (FGU-C) RID, ORCID
Dvořánková, B. (CZ)
Heitz, J. (CZ)
Hnatowicz, Vladimír (UJF-V) RIDSource Title Nuclear Instruments & Methods in Physics Research Section B. - : Elsevier - ISSN 0168-583X
Roč. 225, č. 3 (2004), s. 275-282Number of pages 8 s. Language eng - English Country NL - Netherlands Keywords modified polyethylene ; ion beam ; RGD grafting Subject RIV EI - Biotechnology ; Bionics R&D Projects IAA5011301 GA AV ČR - Academy of Sciences of the Czech Republic (AV ČR) GA106/03/0514 GA ČR - Czech Science Foundation (CSF) CEZ AV0Z5011922 - FGU-C Annotation Polyethylene (PE) was implanted with 15 keV Ar+ and Kr+ ions to the fluences from 3 x 1012 ů 1015 cm-2 and subsequently grafted with amino acid sequence ArgůGlyůAsp (RGD), i.e. a minimum adhesion motif recognized by integrin receptors on cells. Addition of RGD sequence onto double bonds created by the ion irradiation on polymeric chain was observed. The adhesion and proliferation of 3T3 mouse embryonic fibroblasts was increased by ion implantation and additionally also by RGD grafting. Workplace Institute of Physiology Contact Lucie Trajhanová, lucie.trajhanova@fgu.cas.cz, Tel.: 241 062 400 Year of Publishing 2005
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