Radiation affects binding of Fpg repair protein to an abasic site containing DNA
1.
SYSNO ASEP
0104077
Document Type
J - Journal Article
R&D Document Type
Journal Article
Subsidiary J
Ostatní články
Title
Radiation affects binding of Fpg repair protein to an abasic site containing DNA
Title
Vliv záření na vazbu reparačního proteinu Fpg na DNA obsahující abasické místo
Author(s)
Gillard, N. (FR) Běgusová, Marie (UJF-V) Castaing, B. (FR) Spotheim-Maurizot, M. (FR)
Source Title
Radiation Research. - : Radiation Research Society
- ISSN 0033-7587
Roč. 162, č. 5 (2004), s. 566-571
Number of pages
6 s.
Language
eng - English
Country
US - United States
Keywords
ionizing radiation ; DNA ; protein komplex
Subject RIV
BO - Biophysics
R&D Projects
IAA1048103 GA AV ČR - Academy of Sciences of the Czech Republic (AV ČR)
CEZ
AV0Z1048901 - UJF-V
Annotation
The effect of ionizing radiation to a complex between a DNA duplex containing an analogue of an abasic site (the 1,3- propanediol site) and a mutated Lactococcus lactis Fpg (P1G-L1Fpg) lacking strand cleavage activity has been studied. The irradiation hinders Fpg-DNA binding because of the damage to the protein
