Transplants of cells engineered to produce GABA suppress spontaneous seizures
1.
SYSNO ASEP
0102582
Document Type
J - Journal Article
R&D Document Type
Journal Article
Subsidiary J
Ostatní články
Title
Transplants of cells engineered to produce GABA suppress spontaneous seizures
Title
Transplantáty buněk se schopností produkovat GABA potlačují spontánní záchvaty
Author(s)
Thompson, K. W. (US) Suchomelová, Lucie (FGU-C)
Source Title
Epilepsia. - : Wiley
- ISSN 0013-9580
Roč. 45, č. 1 (2004), s. 4-12
Number of pages
9 s.
Language
eng - English
Country
US - United States
Keywords
cell transplantation ; epilepsy ; seizures
Subject RIV
FH - Neurology
CEZ
AV0Z5011922 - FGU-C
Annotation
The purpose of this study was to establish that cells genetically engineered to produce GABA could suppress spontaneous seizures in an accepted model of temporal lobe epilepsy. It was found that these cells have the ability to suppress above mentioned seizures when transplanted into seizure-modulating nuclei