Number of the records: 1

Third Acivity of Bordetella Adenylate Cyclase (AC) Toxin-Hemolysin

SYSNO ASEP	0089187
Document Type	J - Journal Article
R&D Document Type	Journal Article
Subsidiary J	Článek ve WOS
Title	Third Acivity of Bordetella Adenylate Cyclase (AC) Toxin-Hemolysin
Title	Třetí aktivita adenylát cyklázového toxinu-hemolyzinu z Bordetelly .Translokace AC domény přes membránu způsobuje vstup vápníku do CD11b+ monocytů nezávisle na katalytické a hemolytické aktivitě toxinu
Author(s)	Fišer, Radovan (MBU-M)_{RID, ORCID} Mašín, Jiří (MBU-M)_{RID, ORCID} Basler, Marek (MBU-M) Krůšek, Jan (FGU-C)_{RID, ORCID} Špuláková, V. (CZ) Konopásek, Ivo (MBU-M) Šebo, Peter (MBU-M)_{RID, ORCID}
Source Title	Journal of Biological Chemistry. - : Elsevier - ISSN 0021-9258 Roč. 282, č. 5 (2007), s. 2808-2820
Number of pages	13 s.
Language	eng - English
Country	US - United States
Keywords	bordetella ; adenylate cyclase toxin ; enzymatic aktivity
Subject RIV	EE - Microbiology, Virology
R&D Projects	1M0506 GA MŠMT - Ministry of Education, Youth and Sports (MEYS)
	IAA5020406 GA AV ČR - Academy of Sciences of the Czech Republic (AV ČR)
Next source	Framework programmes of European CommissionOther public resources
CEZ	AV0Z50200510 - MBU-M (2005-2011)
	AV0Z50110509 - FGU-C (2005-2011)
UT WOS	000243793900007
Annotation	We report that adenylate cyclase toxin from bacterium Bordetella pertussis causes elevation of [Ca2+]i in CD11b+ J774A.1 monocytic cells by a novel mechanism that is independent of its enzymatic or pore-forming activities and which requires structural integrity and membrane translocation of the AC domain polypeptide as such
Workplace	Institute of Microbiology
Contact	Eliška Spurná, eliska.spurna@biomed.cas.cz, Tel.: 241 062 231
Year of Publishing	2008

Number of the records: 1