SYSNO ASEP | 0048979
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Document Type | J - Journal Article
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R&D Document Type | Journal Article
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Subsidiary J | Ostatní články
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Title | Establishment, growth and in vivo differentiation of a new clonal human cell line, EM-G3, derived from breast cancer progenitors
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Title | Stabilizace, růst a in vivo diferenciace nové klonální lidské buněčné linie, EM-G3, odvozené z progenitorů rakoviny prsu
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Author(s) | Brožová, Markéta (UMG-J) Kleibl, Z. (CZ) Netíková, I. (CZ) Ševčík, J. (CZ) Scholzová, E. (CZ) Březinová, J. (CZ) Chaloupková, Alena (UMG-J) Veselý, Pavel (UMG-J) Dundr, P. (CZ) Zadinová, M. (CZ) Krásná, Luboslava (UMG-J) Matoušková, Eva (UMG-J)
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Source Title | Breast Cancer Research and Treatment
- ISSN 0167-6806
Roč. 103, č. 2 (2007), s. 247-257
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Number of pages | 11 s.
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Language | eng - English
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Country | US - United States
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Keywords | breast cancer ; cell line ; progenitor cells ; differentiation
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Subject RIV | EB - Genetics ; Molecular Biology
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R&D Projects | NR8145 GA MZd - Ministry of Health (MZ)
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| NR8345 GA MZd - Ministry of Health (MZ)
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CEZ | AV0Z50520514 - UMG-J (2005-2011)
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Annotation | A new clonal cell line, EM-G3, was established from a primary lesion of human infiltrating ductal breast carcinoma. The EM-G3 cells formed limited tumors in nu/nu mice organized in primitive ductal-like structures. The results indicate that EM-G3 cells were derived from a premalignant population of common progenitors of luminal and myoepithelial cells.
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Workplace | Institute of Molecular Genetics
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Contact | Nikol Škňouřilová, nikol.sknourilova@img.cas.cz, Tel.: 241 063 217
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Year of Publishing | 2008
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