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Ancient Phylogenetic Beginnings of Immunoglobulin Hypermutation

SYSNO ASEP	0048141
Document Type	J - Journal Article
R&D Document Type	Journal Article
Subsidiary J	Ostatní články
Title	Ancient Phylogenetic Beginnings of Immunoglobulin Hypermutation
Title	Starobylé fylogenetické počátky hypermutace imunoglobulinů
Author(s)	Kubrycht, J. (CZ) Sigler, Karel (MBU-M)_RID Růžička, Michal (FGU-C) Souček, P. (CZ) Borecký, J. (BR) Ježek, Petr (FGU-C)_{RID, ORCID}
Source Title	Journal of Molecular Evolution - ISSN 0022-2844 Roč. 63, - (2006), s. 691-706
Number of pages	16 s.
Language	eng - English
Country	US - United States
Keywords	immunoglobulin ; hypermutation ; antigen
Subject RIV	EE - Microbiology, Virology
CEZ	AV0Z50200510 - MBU-M (2005-2011)
	AV0Z50110509 - FGU-C (2005-2011)
Annotation	Our analysis, based predominantly on primary structure, demonstrates the existence of molecules similar to immunoglobulin (Ig) domains, variable Ig domains (IGv), and antigen receptors (AR) in unicellular organisms and nonvertebrates The results of our analysis are discussed with respect to the possible phylogeny of molecules preceding the hypothetical common antigen receptor ancestor
Workplace	Institute of Microbiology
Contact	Eliška Spurná, eliska.spurna@biomed.cas.cz, Tel.: 241 062 231
Year of Publishing	2007

Number of the records: 1