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Mitochondrial diseases and genetic defects of ATP synthase
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SYSNO ASEP 0048102 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Ostatní články Title Mitochondrial diseases and genetic defects of ATP synthase Title Mitochondriální choroby a genetické defekty ATP syntázy Author(s) Houštěk, Josef (FGU-C) RID, ORCID
Pícková, Andrea (FGU-C)
Vojtíšková, Alena (FGU-C)
Mráček, Tomáš (FGU-C) RID, ORCID
Pecina, Petr (FGU-C) RID, ORCID
Ješina, Pavel (FGU-C)Source Title Biochimica Et Biophysica Acta-Bioenergetics. - : Elsevier - ISSN 0005-2728
Roč. 1757, č. 9-10 (2006), s. 1400-1405Number of pages 6 s. Language eng - English Country NL - Netherlands Keywords mitochondrial diseases ; ATP synthase ; ROS Subject RIV EB - Genetics ; Molecular Biology R&D Projects NR7790 GA MZd - Ministry of Health (MZ) 1M0520 GA MŠMT - Ministry of Education, Youth and Sports (MEYS) CEZ AV0Z50110509 - FGU-C (2005-2011) Annotation Disorders of ATP synthase, the key enzyme of cellular energy provision, can be caused by qualitative changes in enzyme structure and function or by its diminished content. In both cases the ATP production is impaired, mitochondrií retain high values of membrane potential and as a result, mitochondrial ROS production is stimulated Workplace Institute of Physiology Contact Lucie Trajhanová, lucie.trajhanova@fgu.cas.cz, Tel.: 241 062 400 Year of Publishing 2007
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