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Dimethyl sulfoxide potentiates death receptor-mediated apoptosis in the human myeloid leukemia U937 cell line through enhancement of mitochondrial membrane depolarization

SYSNO ASEP	0047641
Document Type	J - Journal Article
R&D Document Type	Journal Article
Subsidiary J	Ostatní články
Title	Dimethyl sulfoxide potentiates death receptor-mediated apoptosis in the human myeloid leukemia U937 cell line through enhancement of mitochondrial membrane depolarization
Title	Dimethylsulfoxid posiluje apoptózu zprostředkovanou receptory smrti v lidské leukemické linii U937 prostřednictvím posílení depolarizace mitochondriální membrány
Author(s)	Vondráček, Jan (BFU-R)_{RID, ORCID} Souček, Karel (BFU-R)_{RID, ORCID} Sheard, M. A. (US) Chramostová, Kateřina (BFU-R) Andrysík, Zdeněk (BFU-R) Hofmanová, Jiřina (BFU-R)_{RID, ORCID} Kozubík, Alois (BFU-R)_{RID, ORCID}
Source Title	Leukemia Research. - : Elsevier - ISSN 0145-2126 Roč. 30, č. 1 (2006), s. 81-89
Number of pages	9 s.
Language	eng - English
Country	GB - United Kingdom
Keywords	human myeloid leukemia ; DMSO ; apoptosis
Subject RIV	BO - Biophysics
R&D Projects	GA524/03/0766 GA ČR - Czech Science Foundation (CSF)
CEZ	AV0Z50040507 - BFU-R (2005-2011)
Annotation	In the present study we described the effects of DMSO on susceptibility of human myeloid leukemia U937 cells towards ligation of distinct death receptors (DRs) were investigated. DMSO sensitized cells towards induction of apoptosis by anti-Fas antibody, tumour necrosis factor-alpha or TNF-related apoptosis-inducing ligand (TRAIL).
Workplace	Institute of Biophysics
Contact	Jana Poláková, polakova@ibp.cz, Tel.: 541 517 244
Year of Publishing	2007

Number of the records: 1