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Modified Bordetella adenylate cyclase comprising or lacking CD11b/CD18 interaction domain and use thereof

SYSNO ASEP	0047008
Document Type	P - Patent
R&D Document Type	Patent or other outcome protected by special legislation
Title	Modified Bordetella adenylate cyclase comprising or lacking CD11b/CD18 interaction domain and use thereof
Title	Modifikovaná adenylát-cykláza která obsahuje či nemá místo pro interakci s CD11b/CD18 a její použití
Author(s)	Leclerc, C. (FR) El-Azami-El-Idrisi, M. (FR) Ladant, D. (FR) Bauche, C. (FR) Šebo, Peter (MBU-M)_{RID, ORCID} Loucká, Jiřina (MBU-M) Osička, Radim (MBU-M)_{RID, ORCID}
Year of issue	2004
Number of pages	65 s.
Patent no. or utility model no. or industrial design no.	EP2004/007811
Date of the patent acceptance	20.06.2004
Name of the patent owner	Institut Pasteur
Language	eng - English
Country	FR - France
Keywords	bordetella ; adenylate cyclase toxins ; CD11b/CD18
Subject RIV	EE - Microbiology, Virology
R&D Projects	IBS5020311 GA AV ČR - Academy of Sciences of the Czech Republic (AV ČR)
CEZ	AV0Z5020903 - MBU-M
Annotation	The invention relates to modified Bordetella adenylate cyclase toxins which are deficient for CD11b/CD18 binding and to the their use in the preparation of pharmaceutical composition for the treatment of whooping cough and/or for the protection against Bordetella infection. The invention also relates to specific fragments of Bordetella adenylate cyclase comprising the CD11b/CD18 interaction domain and to their use, especially for targeting a molecule of interest to CD11b expressing cells
Workplace	Institute of Microbiology
Contact	Eliška Spurná, eliska.spurna@biomed.cas.cz, Tel.: 241 062 231
Year of Publishing	2006

Number of the records: 1