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Hydrolysis of nitriles and amides by filamentous fungi
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SYSNO ASEP 0040410 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Ostatní články Title Hydrolysis of nitriles and amides by filamentous fungi Title Hydrolýza nitrilů a amidů vláknitými houbami Author(s) Kaplan, Ondřej (MBU-M)
Nikolaou, Konstantia (MBU-M)
Charvátová, Andrea (MBU-M)
Martínková, Ludmila (MBU-M) RID, ORCIDSource Title Enzyme and Microbial Technology. - : Elsevier - ISSN 0141-0229
Roč. 38, - (2006), s. 260-264Number of pages 5 s. Language eng - English Country US - United States Keywords biotransformation ; fusarium solani ; penicillium multicolor Subject RIV EE - Microbiology, Virology R&D Projects IAA4020213 GA AV ČR - Academy of Sciences of the Czech Republic (AV ČR) OC D25.001 GA MŠMT - Ministry of Education, Youth and Sports (MEYS) CEZ AV0Z5020903 - MBU-M Annotation Screening of culture collection afforded nitrile-utilizing fungi belonging to genera Aspergillus, Talaromyces and Penicillium. Fusarium solani O1 was enriched from soil using 3-cyanopyridine as the sole source of nitrogen. This strain, and Penicillium multicolor CCF 2244 (the best one of the culture collection strains), showed comparable specific benzonitrile-hydrolyzing activities (0.95 and 0.87 mol of benzoic acid h(-1) mg(-1) of dry cell weight at 28 degrees C, respectively). These fungi showed similar substrate specificities for substituted benzonitriles and heterocyclic nitriles but different pH and temperature optima (pH 8 and 38 degrees C for P multicolor, pH 7 and 48 degrees C for F solani). Amides as by-products were produced from some heterocyclic nitriles. Both fungi showed an amidase activity for nicotinamide Workplace Institute of Microbiology Contact Eliška Spurná, eliska.spurna@biomed.cas.cz, Tel.: 241 062 231 Year of Publishing 2007
Number of the records: 1